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偶也做点贡献吧,关于试管婴儿的成功率 [复制链接]

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只看楼主 倒序阅读 0  发表于: 2005-06-10

引自http://www.cdc.gov/reproductivehealth/ART02/sect2_fig3-13.htm#f6 2002年全美的试管婴儿案例


本人不是专业人士,翻译难免不准,大家凑和看吧


结论:


样本:



  • 85,826 cycles started 启动的周期数



  • 74,519 retrievals 重复的周期数 retrievals可能翻译的不准,可能指的是实际取到卵的情况



  • 69,857 transfers 移植数



  • 29,423 pregnancies 怀孕数



  • 24,324 live-birth deliveries 生产数




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中断周期的原因

  • No or inadequate egg production 84.6% 没有产生卵或没有产生足够的卵
  • Patient withdrew for other reasons 10.2% 由于其它原因病人放弃
  • Too-high response to ovarian stimulation medication 4.3% 卵巢药物刺激过度反应
  • Concurrent illness 0.9% 并发症

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    使用新鲜卵子或囊胚的成功率

    • Pregnancies per cycle 34.3% 每周期怀孕率 haha还是很高的
    • Live births per cycle 28.3% 每周期生产率
    • Live births per retrieval 32.6% 重做的生产率 ?不太明白
    • Live births per transfer 34.8% 每次移植的生产率
    • Singleton live births per cycle 21.1% 每周期的单胎生产
    • Singleton live births per transfer 22.5% 每次移植的单台生产

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    怀孕的情况

  • No pregnancy 65.0% 没有怀孕
  • Ectopic pregnancy 0.7% 异常怀孕
  • Clinical pregnancy 34.3%, which is subdivided as follows: 医学怀孕,具体情况如下
    • Single-fetus pregnancy 19.9% 单胎怀孕
    • Multiple-fetus pregnancy 12.4% 多胎怀孕
    • Not able to determine the number of fetuses because the pregnancy ended in an early miscarriage 2.0%由于早期流产造成的无法确定胚胎数量

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    生产情况:

    • 82.7% 怀孕并成功生产
      • 单胎53.7%
      • 多胎29.0%
    • 16.4% 怀孕没有成功:
      • 流产15.0%
      • 减胎 0.9%
      • Stillbirths 0.5% 生下死婴

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    女方年龄分布情况

    • Age 22, 0.16%
    • Age 23, 0.29%
    • Age 24, 0.51%
    • Age 25, 0.82%
    • Age 26, 1.32%
    • Age 27, 1.87%
    • Age 28, 2.71%
    • Age 29, 3.68%
    • Age 30, 5.02%
    • Age 31, 6.23%
    • Age 32, 6.74%
    • Age 33, 7.24%
    • Age 34, 7.23%
    • Age 35, 7.72%
    • Age 36, 7.28%
    • Age 37, 7.34%
    • Age 38, 7.33%
    • Age 39, 7.11%
    • Age 40, 5.96%
    • Age 41, 5.07%
    • Age 42, 3.97%
    • Age 43, 2.44%
    • Age 44, 1.25%
    • Age 45, 0.52%
    • Age 46, 0.20%

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    不同年龄的成功率

    年龄 怀孕率 生产率 单胎生产率

    • Age 22, Pregnancy rate 38.3%, Live birth rate 33.1%, Singleton live birth rate 25.6%
    • Age 23, Pregnancy rate 47.1%, Live birth rate 38.9%, Singleton live birth rate 26.2%
    • Age 24, Pregnancy rate 44.8%, Live birth rate 39.5%, Singleton live birth rate 25.5%
    • Age 25, Pregnancy rate 43.1%, Live birth rate 37.5%, Singleton live birth rate 24.2%
    • Age 26, Pregnancy rate 42.9%, Live birth rate 38.4%, Singleton live birth rate 23.4%
    • Age 27, Pregnancy rate 45.8%, Live birth rate 40.1%, Singleton live birth rate 23.2%
    • Age 28, Pregnancy rate 42.9%, Live birth rate 37.5%, Singleton live birth rate 22.0%
    • Age 29, Pregnancy rate 45.5%, Live birth rate 39.6%, Singleton live birth rate 23.8%
    • Age 30, Pregnancy rate 42.3%, Live birth rate 36.8%, Singleton live birth rate 22.0%
    • Age 31, Pregnancy rate 44.2%, Live birth rate 38.4%, Singleton live birth rate 22.7%
    • Age 32, Pregnancy rate 43.0%, Live birth rate 37.5%, Singleton live birth rate 23.6%
    • Age 33, Pregnancy rate 41.3%, Live birth rate 35.8%, Singleton live birth rate 22.4%
    • Age 34, Pregnancy rate 39.3%, Live birth rate 33.5%, Singleton live birth rate 20.8%
    • Age 35, Pregnancy rate 38.2%, Live birth rate 32.6%, Singleton live birth rate 20.8%
    • Age 36, Pregnancy rate 37.4%, Live birth rate 31.1%, Singleton live birth rate 19.6%
    • Age 37, Pregnancy rate 33.7%, Live birth rate 28.2%, Singleton live birth rate 18.9%
    • Age 38, Pregnancy rate 31.7%, Live birth rate 24.9%, Singleton live birth rate 17.2%
    • Age 39, Pregnancy rate 26.9%, Live birth rate 19.9%, Singleton live birth rate 14.9%
    • Age 40, Pregnancy rate 23.0%, Live birth rate 16.1%, Singleton live birth rate 12.6%
    • Age 41, Pregnancy rate 18.7%, Live birth rate 12.1%, Singleton live birth rate 9.7%
    • Age 42, Pregnancy rate 15.4%, Live birth rate 9.0%, Singleton live birth rate 7.5%
    • Age 43, Pregnancy rate 11.5%, Live birth rate 6.3%, Singleton live birth rate 6.0%
    • Age 44, Pregnancy rate 6.7%, Live birth rate 2.6%, Singleton live birth rate 2.4%
    • Age 45, Pregnancy rate 2.9%, Live birth rate 1.1%, Singleton live birth rate 0.9%
    • Age 46, Pregnancy rate 2.9%, Live birth rate 0.6%, Singleton live birth rate 0.6%

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    40岁以上妇女的成功率

    • Age 40, Pregnancy rate 23.0%, Live birth rate 16.1%, Singleton live birth rate 12.6%
    • Age 41, Pregnancy rate 18.7%, Live birth rate 12.1%, Singleton live birth rate 9.7%
    • Age 42, Pregnancy rate 15.4%, Live birth rate 9.0%, Singleton live birth rate 7.5%
    • Age 43, Pregnancy rate 11.5%, Live birth rate 6.3 %, Singleton live birth rate 6.0%
    • >Age 43, Pregnancy rate 5.2%, Live birth rate 2.0%, Singleton live birth rate 1.8%

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    不同年龄的流产情况:

    • Age < 25, 13.6%
    • Age 25, 13.0%
    • Age 26, 10.5%
    • Age 27, 12.4%
    • Age 28, 12.6%
    • Age 29, 13.0%
    • Age 30, 13.1%
    • Age 31, 13.1%
    • Age 32, 12.6%
    • Age 33, 13.3%
    • Age 34, 14.7%
    • Age 35, 14.7%
    • Age 36, 16.8%
    • Age 37, 16.2%
    • Age 38, 21.6%
    • Age 39, 26.2%
    • Age 40, 30.2%
    • Age 41, 35.3%
    • Age 42, 41.8%
    • Age 43, 45.0%
    • Age 44, 61.1%
    • Age >44, 64.0%

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    按年龄段统计

    年龄段 重复多次 移植 怀孕 生产

    • <Age 35, Retrieval 91%, Transfer 86%, Pregnancy 43%, Live birth 37%
    • Age 35–37, Retrieval 87%, Transfer 83%, Pregnancy 36%, Live birth 31%
    • Age 38–40, Retrieval 83%, Transfer 78%, Pregnancy 28%, Live birth 21%
    • Age 41–42, Retrieval 80%, Transfer 73%, Pregnancy 17%, Live birth 11%
    • >Age 42, Retrieval 76%, Transfer 65%, Pregnancy 9%, Live birth 4%