多次试管失败的姐妹们，去查查免疫吧 [复制链接]

下一站的幸福，你看过等你宝宝的帖子吗？她也是干燥综合症，如果我没记错的话。在DR.BEER的书中有一章节是关于抗核抗体阳性的。有抗核抗体阳性，提示你可能有自身性免疫系统的问题。但你要综合其他免疫不孕的检查结果，才能知道是否治疗，如何治疗。

美国另一个免疫实验室（RIA）的医生有建议，ANA高的吃强的松就可以了，只有NK高的才要打免疫球蛋白。

发些帖子给懂英文的看看了

vesnaMay 16 2011, 01:30 PM
Doctors please help me
I am currently 5 weeks and 5 days pregnant.I am on lovenox,prednisone 30 mg and IVI-g
*
I have immune issue elevated nk and elevated cytokine level.
My first results BEFORE IVI-G
NK 50:1= 24.5
TNF ALFA =47.7

1.FIRST IVI-G
After IVI-g on 04/18/2011 my results are
NK 50:1=14.8
TNF ALFA=37.9
We were so happy because level dropped
I had transfer on 04/25 and I get pregnant

2.SECOND IVI-G
On 05/04/2011 I had one more IVI-g
Results from that infusion came today but elevated
NK 50:1=31
TNF ALFA 49.5

3.THIRD IVI-G after one week
05/11/2011 results for couple of days

Doctors ,as you can see my levels are rise from the moment I get pregnant.My immune doctor
gave me aggressive IVI-g protocol.I don't have last blood results,they said for
couple of days.Levels from today are after second ivi-g,and they are elevated.Is it normal to be elevated after pregnancy?
I am so scared,I am crying ,please tell me are they gonna kill my baby?
My beta is doubling very nice,we saw sac and yolk sac last week.US for heartbeat
in Wednesday.
I guess levels are little bit lower because I had the third ivi-g after only one
week.
Please help me do I have chance for this for baby
vesna
Geoffrey Sher, MDMay 16 2011, 04:39 PM
Stay the course with the IVIG. Ignore the NKa as there is usually a lag in response anyway. I presume you are taking steroids too along with heparin.

Hopefully all will be well. Please keep me in the loop.

Geoff Sher
vesnaMay 16 2011, 04:46 PM
Thank you my dear Dr.Sher
I am taking prednisone 3 times per day 10 mg,lovenox 2 times, ivi-g
I will know more in Wednesday.
Hug
Vesna
Geoffrey Sher, MDMay 16 2011, 07:57 PM
How much IVIG are you getting. I used to prescribe 40G per infusion at least! Now I have completely supplanted the IVIG with Intralipid.

Good luck!

Geoff Sher
vesnaMay 17 2011, 05:08 AM
[quote name='Geoffrey Sher, MD' date='May 16 2011, 07:57 PM' post='174944']
How much IVIG are you getting. I used to prescribe 40G per infusion at least! Now I have completely supplanted the IVIG with Intralipid.

Good luck!

Geoff Sher
[/quote]
Dear doctor,
I am taking 400mg IVI-G.I am praying that last dose lowered my level.
Tomorrow is big day for us
Thank you for your answer and care
vesna
Geoffrey Sher, MDMay 17 2011, 10:27 AM
The dosage needed is 40 Grams per infusion. 400mg is really completely inadequate.

Geoff Sher
vesnaMay 17 2011, 11:01 AM
[quote name='Geoffrey Sher, MD' date='May 17 2011, 10:27 AM' post='174977']
The dosage needed is 40 Grams per infusion. 400mg is really completely inadequate.

Geoff Sher
[/quote]

Thank you for you answer dear Dr.Sher
Maybe ,I am wrong,I have to check tomorrow
hugs
vesna
Geoffrey Sher, MDMay 17 2011, 03:33 PM
I think you should!

Geoff Sher

    我也是移植5次都没着床，进周2次，2次都腹水，5次都是做冻胚，有2次做过孵化，1次做过囊胚。现在还有8个冻胚在医院。最进一次是2011-5-26号移植，6-9号查血只有0.2，还是没成。
    以前总觉得是运气问题，可运气和概率不可能总不降临到我这，因为看边上的病友还是容易的。所以这次回来就狂查资料，昨天才刚刚发现这个网站，觉得找到支撑。
  
    我也想去查查免疫，上海是在上海红房子医院查的吗？有在那里查的JM吗？查之前要准备什么？要月经干净去，还是月经第几天去好，有要求吗？是夫妻双方查，还是就女方查就行呢？全套的费用要多少？请知情的JM回复哦，急等！！

NK我好象没有查。我查的抗心磷。红狼一套都为阴性。只有ANA1：100阳性。但我吃了一年的强地松。去查还是1：100。1：100也是阴性。也是阳性我就再这个值的低线上掉不下来。不知道怎么办在好。强地松阿司吃的太多明显感觉身体不行了。但我的主制医生也没有给我希望就说在试试吧会成功的。他对我好象也是无能为力。就让我一次次的实验。我的身体；心都在失败中被一点点的击碎。不行就代孕吧。这是我唯一的希望了？我以前有自己怀过两次。为什么试管就失败我找不到答案。也许上辈字是个坏人。这辈子被惩罚！

如果你的ANA高又伴有不孕，可能还有其它免疫的问题。真正造成免疫不孕的罪魁祸首是过于活跃的NK细胞。

楼主好！觉得发现这个帖子太晚了！！！！我今年41岁了，做了3次IVF，前两次都是只有B级胚胎，未成。最近的一次刚刚做完。自然周期取出的一个卵泡，做成了A级胚胎，着床了，第11天HCG: 46，激动地哭了；第13天48，心抽搐；第15天降到了29，都快崩溃了... 在网上疯狂查，好像这个叫生化妊娠吧。我有内异，还有哮喘，所以一定有免疫紊乱的问题。想问一下楼主，NK可以在生化妊娠后检查吗？另外，我小时候得过结核，未经治疗自愈了，但是体内有陈旧性病灶，这样的情况能做免疫治疗吗？很想加楼主的QQ聊，可以吗？

到专门的医院查免疫，根据结果才能定需不需要做治疗，前面的楼有说那家医院最适合做这些检查。搜搜这个论坛的免疫帖子，有些姐妹正在治疗，你和她们交流好了。

谢谢楼主的回复！

下一站的幸福，我昨晚看BEER的书，ANA阳性也是可以用免疫球蛋白的，但这个前提是你要知道自己在其他免疫系统方面出了什么问题，只是说免疫球蛋白这个药是可以用的，只要你的IgA是合格的。