Beer 中心转抄来的关于丈夫DQ alpha 201的资料
"A. DQ Alpha
This test measures whether the DNA of the couple is too closely matched. These tests give you
back two numbers for both members of the couple. In a normal pregnancy the father's DNA in
the baby tells the mother's body to set up a protective reaction around the developing embryo. If
the father's DNA is too closely matched to the mother's, there is a good chance that the embryo
created by them is unable to differentiate itself from the mother's body. The mother's body then
rejects the embryo because it cannot identify the embryo as a baby.
There are two different tests for the DQ, the Alpha and the Beta test. Most patients are only
tested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3,
1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents).
Although there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are
significant, so they break those down to one more decimal. If both the mother-to-be's and the
father-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes
back with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ
molecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce
a placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or
closely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother
and pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility
between mother and baby was far more common in women successfully delivering babies.
DQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it
is also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his
numbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of
his numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his
embryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to
put back more embryos to see if you can produce an embryo that is not DQ 201. If he has both
numbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become
blighted ova."