美国生殖专家与病人的问答 [复制链接]

抗核抗体阳性，要吃类固醇。

nycresident:
   我已买到了免疫球蛋白，规格为5g/瓶，共8瓶。根据你在前几楼帮助翻译的资料写着需要注射40G。
  请问我是该在移植前的第7-10天一次性静脉滴注40G还是分两次滴注每次20G？

我的天，你家是开医院的吧？玩笑。

应该是一次性滴注。等开奖好孕时再滴注40g。每瓶是多少钱呀，英文名是IVIG吧。

nycresident：
     呵呵，呵呵。兵贵神速嘛~

  英文名：Human Immunoglobulin (pH4) for Intravenous Injection.
   中文名：静注人免疫球蛋白（pH4）
  每瓶医院进价：1090元/瓶
  需要冷藏。2--8度
因为今天已经是我周期的第7天了，估计会在第16天排卵，第18天移植。所以想明天就去滴注。

   nycresident     
        现在就等你的确认了。记得在哪里看到过医生建议取卵前注射，那么如果我这个周期取卵应该也没问题吧？
  真的要 谢谢你的好帖，我从来就没考虑过自己的内膜是否会因为反复的宫腔手术等原因产生过多的NK细胞。

是的，很多人打促排针时就打免疫球蛋白。你开奖好孕时可以打20g的量，我看有些帖子就有人那时只打20g的。

引用第64楼安然入睡于2010-12-10 23:11发表的 :
   nycresident     
        现在就等你的确认了。记得在哪里看到过医生建议取卵前注射，那么如果我这个周期取卵应该也没问题吧？
  真的要 谢谢你的好帖，我从来就没考虑过自己的内膜是否会因为反复的宫腔手术等原因产生过多的NK细胞。

如果是人为刮宫流产，NK不会高。如果是自然胎停，胚胎又没问题，那就可能是NK细胞或别的免疫造成的。

这是从老美论坛里抄来的帖子

我从未怀过孕 – 自然的也好，人工授精也好，试管也好，从未成功过，后来做赠卵，也不成功，连着床一次都没有过。我们几乎都要放弃了，后来听到免疫不孕这么一说，就去做了检查，结果我的NK细胞活性过高。

 

我决定再做最后一次赠卵试管尝试，那时我已经43岁。尽管我做自卵试管时卵子质量、胚胎质量看上去都很好，医生仍建议我做赠卵，因为年纪大了，卵子不正常的几率太高了。

 

我在移植前2个星期打了一次免疫球蛋白，剂量40g。开奖好孕了，怀了双胎，其中一个停育了，生下一个女儿。验血查出怀孕后，我又连打了三次免疫球蛋白，每次剂量20g，第一次是在开奖的当天，以后两次是每隔4个星期。四次免疫球蛋白一共花了我1万美元。

 

后来我又做冷冻移植，还是按前面的方案打免疫球蛋白，又怀孕了，现在已经11周。这次我只打三次免疫球蛋白，省掉了最后一次的20g一针，所以这回的费用是8000美元。



I couldn't get pg to save my life -- not naturally, IUIs, GIFTs with my eggs, IVFs with my eggs, and finally DE -- nothing, not a single positive beta. We were about to give up but had heard about immune system testing, and I came out positive for elevated NK cells.

Decided to try one more time, and stayed with DE since I was 43, even though I had been having good results with my own eggs -- decent numbers, good-looking embryos. The doctor suggested because of my age not to go back to my eggs, so we went DE again.

Had an IVIg treatment two weeks before transfer (40 gr - comes out to about $1,000/10 gr). Got pg, had twins and then a vanishing. DD is 4 years old.

I had to have another IVIg (20 gr) right after positive beta, then two more (20 gr/each) for a total of four treatments, all spaced four weeks apart. Total cost, not covered by insurance, about $10,000 in the US.

Decided to try for a sibling. Same protocol exactly, different donor. Got pg, had twins who just turned two. Another $10,000. Cha-ching.

Decided to use our last frozen embies this year, same IVIg protocol, got pg. Am almost 11 weeks, and had last IVIg treatment two weeks ago. This time, they only said I had to do three -- I think they have decided that four was not necessary, esp given the expense. So this cycle was "only" $8,000 for the IVIg (40/20/20).

As you can see, I am a true believer -- it was not just DE that ended up working, because it DIDN'T work the first time, from a very fertile woman (has five kids from two husbands!) It was only after I went to IVIg that I got pg -- three tries out of three, with two different donors!

安然：免疫球蛋白是你自己买的，还是医生开给你的？40G岂不是要8000多元？ nycresident 说5000多元，贵了这么多？

引用第68楼凤眼果于2010-12-11 19:24发表的 :
安然：免疫球蛋白是你自己买的，还是医生开给你的？40G岂不是要8000多元？ nycresident 说5000多元，贵了这么多？

我其实不知道价格，所以才会问。